Bisphosphonates are a therapeutic class that addresses only the bone problem of the postmenopausal women.
They provide the treatment and prevention for Osteoporosis, but they also induce a lot of gastric problems.
In addition, the patient has to stand upright for half an hour, and not eat or drink anything for 30 minutes before and after taking the drug.
Calcitonin: Calcitonin is the hormone produced by the Thyroid Gland. It is a natural pain killer and prevents Osteoporosis. There is no existing data on the treatment of Osteoporosis, only on preventative treatment.
The dilemma of Oestrogen:
The decrease in Oestrogen associated with menopause is an important factor in the development of osteoporosis. HRT is good for short term treatment of the menopause. It helps to combat the symptoms of the menopause – hot flushes, night sweats, depression and mood swings.
– 1. Women with Breast Cancer
– 2. Deep vein Thrombosis – D.V.T
– 3. Liver problems
Complications of HRT:
– 1. Causes tender breasts
– 2. Spotting / bleeding from the Uterus
– 3. Fluid retention and increase in weight.
Serum: (Selective Estrogen Receptor Modulator)
These are a new therapeutic class for the management of Osteoporosis. Evista provides postmenopausal women with treatment and prevention for Osteoporosis. In addition, Evista has a beneficial effect on the heart, it has a breast cancer protective effect and is safe on the Uterus.
To summarize, Evista is a solution for long term risk, however it does not provide a solution for the short term symptoms.
Impact on bone:
On the skeletal system, Evista builds healthy bones by increasing bone mass and stops the thinning of the bones. It also reduces fracture risk by 68% after one year of treatment.
Afraid of the side effects?
On the Uterus Evista is very safe.
On the Breast, Evista has a protective effect against breast cancer.
Whom should not take Evista?
Patients with a history of deep venous thrombosis
Complications of Evista :
Patients might experience hot flushes & Leg cramps
Ease of use: – One tablet per day, regardless of meals
– Can be taken at any time of the day
– There are no interruptions to the daily routine
Osteoporotic fractures have considerable negative impact on health-related quality of life among the elderly. Because the number of hip fracture patients is rising and increased dependency in older patients is becoming more common, costs of long – term care is expected to rise.
The prevention of osteoporosis and osteoporictic fractures is an important priority and constitutes the only cost effective approach to this disease. Therapy that decreases bone loss could greatly reduce osteoporictic fracture risk, counteracting the exponential increase in risk with age. Measures to reduce falls in the elderly could also reduce the incidence of fractures.